Endometrial receptivity is the period of time when the endometrium is ready for embryo implantation. This typically occurs from days 19-21 during the menstrual cycle of fertile women. This interval of receptivity is also referred to as the window of implantation (WOI).
Large scale studies have shown that 30% of infertility patients have a displaced window of implantation (WOI). One of the main causes of implantation failure is the lack of synchronization between embryo and endometrium. MIRA is able to assess the endometrial receptivity in order to determine the optimal time for embryo transfer.
Successful implantation rate*
What can MIRA tell me?
A comprehensive report will be provided to you and your physician that identifies your optimal window of implantation and advises you on the best time to perform personalized embryo transfer.
Receptive: Best Time to Implant
In the Window of Implantation (WOI)
A Receptive result on your report indicates that the time of the tissue biopsy was the optimal time for embryo transfer and the same conditions and timing can be used during your subsequent treatment cycles for the most favorable personalized embryo transfer conditions.
Non-receptive: Adjust Implantation Time
NOT in the Window of Implantation (WOI)
A Non-Receptive result on your report indicates that the time of the tissue biopsy was not in the optimal time period for embryo transfer and that the timing of your embryo transfer should be changed in order to increase the chance of successful implantation.
Inconclusive – The analysis could not determine the optimal time for embryo transfer. This could be the result of an exceptionally low quality or low quantity biopsy sample. A member of MIRA’s team will be in contact with your physician in order to make the necessary adjustments to the timing of the endometrial biopsy. The biopsy should be repeated within the suggested time for endometrial biopsy. An inconclusive result happens in less than 1% of results.
Should I take this test?
A displaced WOI can happen to anyone regardless of age
You should take this test if you
Plan on undergoing an IVF treatment
Have undergone multiple IVF treatments with no success
MIRA has performed thousands of sample tests, with less than 5% resampling rate, significantly lower than the 15% resampling rate of competing tests.
MIRA has a 99% prediction rate of receptivity (WOI), with a successful implantation rate of over 70%.
Trusted by professionals and clinics around the world, MIRA undergoes continuous advancements to enhance the accuracy of the test.
What is MIRA’s testing process?
The testing process can be done directly at your fertility doctor’s clinic. Your doctor will use the tools provided in the MIRA sample submission kit to collect your endometrial biopsy sample for the analysis.
Ask Your Fertility Doctor
Speak to your fertility doctor about taking the MIRA test. We have provided clinics with comprehensive sample submission kits to help your needs.
Book an Appointment
Ask your doctor to schedule your endometrial biopsy appointment based on either natural cycles or hormone replacement therapy cycles*.
Fill out the Forms
Fill out the Sample Submission and Consent Form (included in the kit) on the day of your biopsy.
After the endometrial biopsy is taken, your sample will be shipped to a MIRA laboratory to be processed.
Wait for the Results
Once available, your MIRA report results will be emailed to you and your fertility doctor.
Follow up Appointment
Your fertility doctor will explain your MIRA report results to you during a follow up appointment.
Endometrial biopsy should be taken either:
1. After 5 days (120 hours) of progesterone administration in a hormone replacement therapy (HRT) cycle.
2. Or, after 7 days (168 hours) from hCG administration in a natural cycle.
Undergoing the MIRA test will not guarantee a successful implantation, as there are many other factors that can affect a successful implant. However, understanding your endometrial receptivity will help your fertility doctor eliminate WOI as a reason for implantation failure.